摘要
背景:个性化药物正在成为普遍的努力,在正确的时间为正确的患者提供正确的治疗。但是,它缺乏对非医疗因素的考虑,如患者的偏好和社会心理因素,这些都是不应该避免的。 目的和方法:本研究总结了炎症性肠病(IBD)患者在疾病不同阶段经历的心理社会困难,以确定评估心理社会危险因素和个性化治疗策略的方法。为了实现这一目标,量化文献与患者的观点相匹配,提供IBD患者经历的心理社会风险因素的广泛概述。 结果:定量结果为IBD的特定心理社会危险因素和心理社会干预结果不足提供了有力证据,但是缺乏个性化的研究,手段和干预措施,增加了研究结果与临床实践之间的距离。与此同时,定性研究结果显示出重要的意义,尽管定量研究揭示了掩盖的信息(例如身份恢复,争夺控制权,性关切),这可以作为进一步探索的出发点。 结论:本研究表明需要采取个体化治疗方法并提供心理治疗,同时考虑患者的经历和偏好。
关键词: 临床心理学,炎症性肠病,混合方法,个性化药物,心理相关因素,心理干预。
图形摘要
Current Drug Targets
Title:Personalizing Psychological Treatment Along the IBD Journey: From Diagnosis to Surgery
Volume: 19 Issue: 7
关键词: 临床心理学,炎症性肠病,混合方法,个性化药物,心理相关因素,心理干预。
摘要: Background: Personalized medicine is becoming a widespread effort to provide the right treatment to the right patient at the right time. However, it lacks of consideration for nonmedical factors, such as patient preferences and psychosocial factors, which should not be avoided.
Objective and Methods: The present study summarizes the psychosocial difficulties experienced by patients with inflammatory bowel disease (IBD) during different phases of the disease in order to identify methods to assess psychosocial risk factors and personalize treatment strategies. To reach this goal, the quantitative literature is matched with the patients' perspective, offering a broad overview of psychosocial risk factors that IBD patients experience.
Results: Quantitative results offer strong evidences for specific psychosocial risk factors in IBD and for weak results of psychosocial interventions, but show a lack of individually tailored researches, instruments and interventions, increasing the distance between the research findings and clinical practice. At the same time, qualitative findings show important, though veiled information uncovered by the quantitative research (e.g., identity recovery, fight for control, sexual concerns), which may be used as a starting point for further explorations.
Conclusion: The present study suggests a need to adopt individualized therapeutic approach and deliver psychological therapies while taking into account patients' experiences and preferences.
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Cite this article as:
Personalizing Psychological Treatment Along the IBD Journey: From Diagnosis to Surgery, Current Drug Targets 2018; 19 (7) . https://dx.doi.org/10.2174/1389450118666170502142939
DOI https://dx.doi.org/10.2174/1389450118666170502142939 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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