Abstract
Immobilization of biomolecules in porous supports, especially in silica matrices, is probably one of the most successful processes in biomaterials synthesis in the last three decades. The flexibility and versatility offered by the sol-gel process, ensured its leading position in the biomolecules immobilization. Functionalization with organic groups of the silica precursors leads to so-called organically modified silica gels. While there are many studies published recently about organically modified silica gels, the relationship between the functionalized support properties and the biomolecules activity is still poorly understood. The aim of this review is to summarize the available results on the influence of the organic functionalization of the silica support on the performance of immobilized biomolecules.
Keywords: sol-gel technique, organically modified silica, biomolecule encapsulation, catalysis, silica matrices, silica gels.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
22
2
1
2