摘要
纳米医学近年来得到了广泛的发展。在纳米医学系统中,纳米尺度和纳米结构的功能材料被用于在分子水平上操纵人类生物系统。癌症成像和治疗。新型纳米结构功能材料由纳米脂质体、球、胶束、胶囊、乳液、悬浮液和噬菌体组成。几种功能性纳米颗粒例如脂基和聚合物基材料被证明是药物的载体和成像剂。这些材料具有生物降解性、生物相容性和良好的生物分布性,副作用小,毒性低。此外,具有这些材料涂层的杂化材料具有独特的电学、光学和磁性。本文对其应用研究进行了综述。功能材料,特别是纳米粒子作为成像造影剂、肿瘤治疗药物和多功能药物的研究,本文综述了热疗一体化治疗的研究进展。NTS治疗肝癌和脑癌。
关键词: 纳米材料,生物材料,癌症,影像学,治疗,热疗法,肝脏肿瘤,大脑胶质瘤病。
Current Medicinal Chemistry
Title:Nanoscale Functional Biomaterials for Cancer Theranostics
Volume: 25 Issue: 25
关键词: 纳米材料,生物材料,癌症,影像学,治疗,热疗法,肝脏肿瘤,大脑胶质瘤病。
摘要: Nanomedicine is widely developed in recent years. In nanomedicine system, nanoscale and nanostructured functional materials are used to manipulate the human biology systems at the molecular level for cancer imaging and therapy. New nanostructure based functional materials consist of nanoscale liposomes, spheres, micelles, capsules, emulsion, suspension and phamacosomes. Several functional nanoparticles such as lipidbased and polymer-based materials are demonstrated to be drug delivery vehicles and imaging agents. These materials are biodegradable, biocompatible and have better biodistribution, lower side effect and lower toxicity. In addition, hybrids with these materials coating provide uniquely electrical, optical and magnetic properties. This review discusses the research on the applications of functional materials, especially nanoparticles as imaging contrast agents, cancer therapeutic agents and multi-functional agents and this review focused on the theranostic integration treatments on liver cancer and brain cancer.
Export Options
About this article
Cite this article as:
Nanoscale Functional Biomaterials for Cancer Theranostics, Current Medicinal Chemistry 2018; 25 (25) . https://dx.doi.org/10.2174/0929867324666170406111036
DOI https://dx.doi.org/10.2174/0929867324666170406111036 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
A Quantitative Proteomics Approach in the Study of MicroRNA 181a in HepG2 Cells
Current Proteomics Parallel Gene Expression Profiling of Mantle Cell Lymphoma – How Do We Transform ´Omics Data into Clinical Practice
Current Genomics Direct-Acting Antivirals for Hepatitis C Virus (HCV): The Progress Continues
Current Drug Targets FAK and Nanog Cross Talk with p53 in Cancer Stem Cells
Anti-Cancer Agents in Medicinal Chemistry Has Selenium a Chemopreventive Effect on Hepatocellular Carcinoma?
Mini-Reviews in Medicinal Chemistry Evaluation of the Possible Contribution of Antioxidants Administration in Metabolic Syndrome
Current Pharmaceutical Design Nucleoside Transport as a Potential Target for Chemotherapy in Malaria
Current Pharmaceutical Design Neuroprotection by Natural Polyphenols: Molecular Mechanisms
Central Nervous System Agents in Medicinal Chemistry Hepatocellular Carcinoma Outside of the Milan Criteria
Current Cancer Therapy Reviews Hypoxia Responsive Drug Delivery Systems in Tumor Therapy
Current Pharmaceutical Design T Cell Tuning for Tumour Therapy: Enhancing Effector Function and Memory Potential of Therapeutic T cells
Current Gene Therapy Dasatinib: An Anti-Tumour Agent via Src Inhibition
Current Drug Targets Stem Cell Differentiation Stage Factors from Zebrafish Embryo: A Novel Strategy to Modulate the Fate of Normal and Pathological Human (Stem) Cells
Current Pharmaceutical Biotechnology Potential Role of PKC Inhibitors in the Treatment of Hematological Malignancies
Current Pharmaceutical Design Advances in Regulating Tumorigenicity and Metastasis of Cancer Through TrkB Signaling
Current Cancer Drug Targets Stem Cells, Cancer, Liver, and Liver Cancer Stem Cells: Finding a Way Out of the Labyrinth...
Current Cancer Drug Targets The gp130 Receptor Cytokine Family: Regulators of Adipocyte Development and Function
Current Pharmaceutical Design MicroRNAs - Key Players in Haematopoiesis
Current Signal Transduction Therapy Senescence and Cell Death Pathways and Their Role in Cancer Therapeutic Outcome
Current Medicinal Chemistry MicroRNAs in the Pathobiology of Multiple Myeloma
Current Cancer Drug Targets