摘要
背景:由于纳米材料具有吸引人的物理化学性质,因此已经将大量研究工作引导至生物和生物医学应用的发展。特别是,锌纳米材料(nZnOs)在医疗和制药领域显示出巨大的潜力,并作为新型抗菌治疗的工具,从而发挥其独特的抗菌作用。 方法:我们使用数据库进行文献检索,以检索与nZnOs在疾病诊断和治疗中的合成,性质和当前应用相关的相关文章。本评价共选出86篇出版物。 结果:除了合成nZnOs的性质和方法的研究之外,许多研究集中于nZnOs作为递送剂,生物传感器和抗微生物剂以及生物成像的应用。 结论:本综述概述了nZnOs潜在用作关键药物的当前发展情况。然而,需要更全面的研究来更好地评估nZnOs在纳米医学领域的宝贵贡献和安全性。
关键词: 氧化锌纳米材料,诊断,治疗,纳米医学,生物医学应用,治疗剂。
Current Medicinal Chemistry
Title:Biomedical Applications of Nanomaterials as Therapeutics
Volume: 25 Issue: 12
关键词: 氧化锌纳米材料,诊断,治疗,纳米医学,生物医学应用,治疗剂。
摘要: Background: As nanomaterials possess attractive physicochemical properties, immense research efforts have been channeled towards their development for biological and biomedical applications. In particular, zinc nanomaterials (nZnOs) have shown great potential for use in in the medical and pharmaceutical fields, and as tools for novel antimicrobial treatment, thereby capitalizing on their unique antimicrobial effects.
Methods: We conducted a literature search using databases to retrieve the relevant articles related to the synthesis, properties and current applications of nZnOs in the diagnosis and treatment of diseases. A total of 86 publications were selected for inclusion in this review.
Results: Besides studies on the properties and the methodology for the synthesis of nZnOs, many studies have focused on the application of nZnOs as delivery agents, biosensors and antimicrobial agents, as well as in bioimaging.
Conclusion: This review gives an overview of the current development of nZnOs for their potential use as theranostic agents. However, more comprehensive studies are needed to better assess the valuable contributions and the safety of nZnOs in nanomedicine.
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Cite this article as:
Biomedical Applications of Nanomaterials as Therapeutics, Current Medicinal Chemistry 2018; 25 (12) . https://dx.doi.org/10.2174/0929867324666170331120328
DOI https://dx.doi.org/10.2174/0929867324666170331120328 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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