Abstract
Stereochemistry has occupied a great role in the manufacture and development of pharmaceuticals. Chiral properties play an important role in the determination of pharmacological actions of the drug. In recent years, there is a considerable interest in chiral separation to isolate and examine both enantiomers. This article provides an overview about the stereochemistry and its role in drugs, and also, offers approved isolation methods for enantiomeric pairs.
Keywords: Chirality, stereoisomer, enantiomer, pharmacology, chiral separation, chiral drug.
Graphical Abstract
Infectious Disorders - Drug Targets
Title:Role of Chirality in Drugs: An Overview
Volume: 18 Issue: 2
Author(s): Hourieh Alkadi*Rajwa Jbeily
Affiliation:
- Department of Pharmaceutical Chemistry & Drug Control, Faculty of Pharmacy, Arab International University,Syrian Arab Republic
Keywords: Chirality, stereoisomer, enantiomer, pharmacology, chiral separation, chiral drug.
Abstract: Stereochemistry has occupied a great role in the manufacture and development of pharmaceuticals. Chiral properties play an important role in the determination of pharmacological actions of the drug. In recent years, there is a considerable interest in chiral separation to isolate and examine both enantiomers. This article provides an overview about the stereochemistry and its role in drugs, and also, offers approved isolation methods for enantiomeric pairs.
Export Options
About this article
Cite this article as:
Alkadi Hourieh *, Jbeily Rajwa , Role of Chirality in Drugs: An Overview, Infectious Disorders - Drug Targets 2018; 18 (2) . https://dx.doi.org/10.2174/1871526517666170329123845
DOI https://dx.doi.org/10.2174/1871526517666170329123845 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements