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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Review Article

An Overview of Currently Available Antimalarials

Author(s): Nikolay Yu. Gorobets*, Yuriy V. Sedash, Brajendra K. Singh, Poonam and Brijesh Rathi*

Volume 17, Issue 19, 2017

Page: [2143 - 2157] Pages: 15

DOI: 10.2174/1568026617666170130123520

Price: $65

Abstract

Background: Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial therapy increases threat to the global public health.

Objective: Overview of currently available antimalarials.

Method: Literary survey.

Results: The summarized data about different types of antimalarial therapies and their efficiency and modes of action.

Conclusion: Despite the seemingly large number of the drugs currently available for malaria treatment, this arsenal is limited due to the narrow variation of their mechanism of action.

Keywords: Malaria, Antimalarial drugs, Drug resistance, Mechanism of action, Antimalarial therapy, Plasmodium.

Graphical Abstract


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