摘要
发达国家心血管疾病(CVD)仍然是死亡的首要原因。此外,导致CVD发展的心血管危险因素远远不会减少。因此,目前实施的预防和治疗管理显然不足以阻止这一流行病。在这种情况下,鉴于其与CVD的关联,已经出现了对脂蛋白(a)[Lp(a)]的兴趣。本文旨在回顾Lp(a)生物学的基础和临床方面。具体来说,本次回顾考虑了生活方式,激素等生理或病理状况对Lp(a)血浆浓度的影响的现状,这可能减轻该脂蛋白的有害影响。
关键词: 脂蛋白(a),心血管疾病,生活方式,激素,饮食,运动。
Current Medicinal Chemistry
Title:Lipoprotein (a) Management: Lifestyle and Hormones
Volume: 24 Issue: 10
关键词: 脂蛋白(a),心血管疾病,生活方式,激素,饮食,运动。
摘要: Cardiovascular disease (CVD) continues to be the first cause of mortality in developed countries. Moreover, far from diminishing, the cardiovascular risk factors leading towards the development of CVD are on the rise. Therefore, the preventive and therapeutic management which is currently in place is clearly not enough to stop this pandemic. In this context, a major resurgence in interest in lipoprotein (a) [Lp(a)] has occurred in light of its association with CVD. This series aims to review the basic and clinical aspects of Lp(a) biology. Specifically, the present review considers the current situation regarding the influence of lifestyle, hormones and other physiological or pathological conditions on Lp(a) plasma concentrations which might mitigate the harmful effects of this lipoprotein.
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Cite this article as:
Lipoprotein (a) Management: Lifestyle and Hormones, Current Medicinal Chemistry 2017; 24 (10) . https://dx.doi.org/10.2174/0929867324666170124144427
DOI https://dx.doi.org/10.2174/0929867324666170124144427 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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