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Current Traditional Medicine

Editor-in-Chief

ISSN (Print): 2215-0838
ISSN (Online): 2215-0846

Review Article

Paeonol, a Powerful Natural Product with Broad Biological Spectra by Inhibiting Inflammatory Pathway

Author(s): Bixi Tang, Cai-Yun Peng, Kwame Oteng Darko, Ting Tao, Yanjun Huang, Qiongli Su and Xiaoping Yang

Volume 2, Issue 2, 2016

Page: [72 - 79] Pages: 8

DOI: 10.2174/2215083802666161025162252

Price: $65

Abstract

Paeonol, a naturally existing compound found in Chinese traditional medicinal herb Cortex Moutan, the root bark of Paeonia suffruticosa Andr., has shown anticancer, antiinflammatory and anti-cardiovascular disease activities. These biological activities largely rely on the mechanisms underlying. It has been shown that these biological activities of paeonol are largely related to the inflammatory NF-κB cell signaling pathways. In this minireview, we are the first to summarize biological activities and associated pathways of paeonol.

Keywords: Antitumor, anti-inflammatory, anticancer, in vivo, in vitro, paeonol.

Graphical Abstract


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