摘要
糖尿病是一个综合疾病每天影响着越来越多的人。尤其,糖尿病在妊娠期是一个既普通又不容忽视同时是一个复杂的疾病。对于妊娠期的孕妇和新生儿说,妊娠期糖尿病都增加了胎儿和母体的发病率和死亡率。胰岛素和降血糖药都能治疗糖尿病,但是同样需要日常的锻炼和足够的饮食。此外,互助治疗如药用植物被广泛用于降低糖尿病引起的高血糖,无论是内部或外部的妊娠中。然而,为了证实可能的影响和胎儿和妈妈的健康,研究检测植物用于治疗糖尿病是很有必要的。这篇文章的目的是为了调查运用于世界各地植物的物种和他们的使用治疗情况。搜索一篇包含“糖尿病和妊娠期”相关的文献能得到31272篇文章,但是只有12(0.0038%)篇是关于药用植物的,表明在这个领域的研究少之又少。在这些研究药用植物的文章中,一半选用植物叶子,科学研究试图复制各种人群在茶这种形势中的组成。此外,超过90%的研究利用实验性动物评估那些可能含有有毒成分的药用植物中的物质在胎儿和母体中的安全性。因此,一旦基于毒理学研究建立成熟安全的植物物质成分研究,植物用于补充传统糖尿病治疗才真正成为可能。
关键词: 糖尿病,妊娠期,药用植物,草药,治疗,评论。
Current Medicinal Chemistry
Title:Medicinal Plants for Diabetes Treatment During Pregnancy
Volume: 24 Issue: 4
关键词: 糖尿病,妊娠期,药用植物,草药,治疗,评论。
摘要: Diabetes mellitus is a syndrome of great importance that affects an increasing number of people every day. In particular, diabetes is a common and important disease during pregnancy and is marked by complications, both fetal and maternal, that increase the risks of morbidity and mortality for diabetic pregnant women and their offspring. Drugs such as insulin and hypoglycemic drugs are given to treat diabetes, but regular exercise and adequate diet have also been indicated. Furthermore, coadjutant therapies such as medicinal plants are popularly used to reduce diabetes-induced hyperglycemia, either within or outside the context of pregnancy. However, studies examining plant use for diabetes treatment are necessary to confirm its possible effects and its safety for the mother and fetus. The objective of this literature review was to conduct a survey of plant species that are utilized worldwide and their stated therapeutic uses. A literature search was performed using the terms “diabetes and pregnancy”, which resulted in the identification of 31,272 articles. Of these studies, only 12 (0.0038%) were related to medicinal plants, demonstrating that there has been little investigation into this issue. Of the papers analyzed in this review, half evaluated plant leaves, indicating that these scientific studies attempted to reproduce the preparations commonly used by various populations, i.e., in the form of tea. Additionally, more than 90% of studies utilized experimental animals to evaluate the maternal-fetal safety of medicinal plant substances that may potentially be dangerous for humans. Thus, once confidence levels for plant-derived substances are established based on toxicological analyses and safety is confirmed, it is possible that plants will be used to complement conventional diabetes therapies.
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Cite this article as:
Medicinal Plants for Diabetes Treatment During Pregnancy, Current Medicinal Chemistry 2017; 24 (4) . https://dx.doi.org/10.2174/0929867323666161003122914
DOI https://dx.doi.org/10.2174/0929867323666161003122914 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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