Secondary Metabolites from Acremonium Fungi: Diverse Structures and Bioactivities

Title:Secondary Metabolites from Acremonium Fungi: Diverse Structures and Bioactivities

Volume: 17 Issue: 7

Author(s): Jin Tian, Daowan Lai*Ligang Zhou*

Affiliation:

• Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193,China

• Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193,India

Keywords: Acromonium fungi, alkaloids, bioactivities, β-lactam antibiotic, marine organisms, secondary metabolites.

Abstract: Background: Acremonium fungi have been isolated from various sources, such as soil, plants, and marine organisms.

Method: The species in Acremonium have been proved to be rich sources of novel and bioactive secondary metabolites. Up to now, 356 metabolites belonging to steroids (6 compounds), terpenoids (86), meroterpenoids (66), polyketides (89), alkaloids (28), peptides (75), and miscellaneous types (6) have been isolated from Acremonium fungi. These metabolites displayed a wide range of biological activities including antimicrobial, cytotoxic, antitumor, immunosuppressive, antioxidant, antiinflammatory, antimalarial, phytotoxic, tremorgenic, antiviral, neuritogenic, insecticidal and enzymesinhibiting activities.

Conclusion: This review highlights the structures and bioactivities of the secondary metabolites from Acremonium fungi reported until July 2016.

Cite this article as:

Tian Jin, Lai Daowan*, Zhou Ligang*, Secondary Metabolites from Acremonium Fungi: Diverse Structures and Bioactivities, Mini-Reviews in Medicinal Chemistry 2017; 17 (7) . https://dx.doi.org/10.2174/1389557516666160914194134

DOI https://dx.doi.org/10.2174/1389557516666160914194134	Print ISSN 1389-5575
Publisher Name Bentham Science Publisher	Online ISSN 1875-5607