Medical and Dental Implications of Down Syndrome: A Review Part 1: General and Craniofacial Characteristic

Title:Medical and Dental Implications of Down Syndrome: A Review Part 1: General and Craniofacial Characteristic

Volume: 3 Issue: 3

Author(s): Batool Ghaith, Mawlood B. Kowash and Manal El-Halabi

Affiliation:

Keywords: Down syndrome, craniofacial anomalies, atlanto-axial joint instability, obstructive sleep apnoea.

Abstract: Down syndrome (DS) is a genetic disorder characterized by the presence of three chromosomes instead of two, specifically chromosome No. 21. The special needs status of DS individuals makes them more prone to several medical conditions such as congenital heart disease, gastrointestinal tract anomalies, immunodeficiency, visual impairment, skeletal defects, audiological dysfunction, seizures, acute leukaemia and thyroid disorders. A thorough knowledge of the unusual medical and orofacial abnormalities and their implications is crucial for a successful dental preventive and treatment planning. This paper provides an updated review of DS definition, etiology, epidemiology, medical problems and dentofacial abnormalities.

Cite this article as:

Ghaith Batool, Kowash B. Mawlood and El-Halabi Manal, Medical and Dental Implications of Down Syndrome: A Review Part 1: General and Craniofacial Characteristic, Applied Clinical Research, Clinical Trials and Regulatory Affairs 2016; 3 (3) . https://dx.doi.org/10.2174/2213476X03666160901125732

DOI https://dx.doi.org/10.2174/2213476X03666160901125732	Print ISSN 2213-476X
Publisher Name Bentham Science Publisher	Online ISSN 2213-4778