How Valid is Placebo in the Indian Setting?

Title:How Valid is Placebo in the Indian Setting?

Volume: 17 Issue: 2

Author(s): Himanshu Sharma*Bharti Sharma

Affiliation:

• PS Medical College & SK Hospital, Karamsad-388325, Anand, Gujarat,India

Keywords: Clinical practice, deception, ethics, indian setting, placebo, randomized controlled trials.

Abstract: Background: The Placebo is defined as an inert substance with a potent therapeutic effect. Its effect is attributed to its psychological and neurobiological effect. Its use in Psychiatric drug practice, drug trials and clinical practice is common, especially in India. Currently there is a debate whether to use it or not as there are ethical, moral and legal issues. Also, its mechanism of action is not known.

Discussion: The Indian Psychiatry scenario is muddled in relation to use of placebo in Randomized Controlled Trials or Psychiatric clinical practice. Despite the scepticism associated with this phenomenon physicians get influenced by it. The present article focuses on the reviews done so far on the efficacy and use of placebo and also the points in favour and against the same in drug trials and psychiatric clinical practice.

Summary: A number of controversies are associated with this biologically inert substance which has no pharmacological role. Currently in medical sciences many scientific studies have been done solely on placebo. The development in this area may have future implications for further research.

Cite this article as:

Sharma Himanshu*, Sharma Bharti, How Valid is Placebo in the Indian Setting?, Central Nervous System Agents in Medicinal Chemistry 2017; 17 (2) . https://dx.doi.org/10.2174/1871524916666160810162420

DOI https://dx.doi.org/10.2174/1871524916666160810162420	Print ISSN 1871-5249
Publisher Name Bentham Science Publisher	Online ISSN 1875-6166