用于肽和蛋白质生物标志物选择性分析的磁性材料

Title:Magnetic Materials for the Selective Analysis of Peptide and Protein Biomarkers

Volume: 24 Issue: 5

关键词: 磁珠，磁性固定相萃取，蛋白质生物标记，新材料，生物标志物富集，生物标志物定量。

摘要: This mini-review article provides an overview on the use of magnetic materials for the analysis of protein biomarkers. In particular, the advantage provided by magnetic solid phase extraction will be discussed with selected examples, considering untargeted analysis for screening new biomarker proteins and targeted investigation on known and suggested new biomarkers. Aspects, such as enrichment efficiency over conventional techniques, ease of use, functionalization versatility and automation will be considered, together with quantification and deeper structure elucidation provided by coupling selective or specific enrichment to powerful characterization techniques, such as mass spectrometry.

Cite this article as:

Magnetic Materials for the Selective Analysis of Peptide and Protein Biomarkers, Current Medicinal Chemistry 2017; 24 (5) . https://dx.doi.org/10.2174/0929867323666160805121905