Bioinspired Platform Conjugated Active Drug Delivery

Title:Bioinspired Platform Conjugated Active Drug Delivery

Volume: 19 Issue: 4

Author(s): Jingxin Shao, Mingjun Xuan, Qiang He*Luru Dai*

Affiliation:

• Key Laboratory of Micro-systems and Micro-structure Manufacturing, Ministry of Education, MicroNanotechnology Research Centre, Harbin Institute of Technology, Harbin,China

• CAS Key Lab for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing,China

Keywords: Bioinspired, active targeting, drug delivery, molecular motor, bio-camouflage, self-propelled nanomotors.

Abstract: Background: The rapid emergence of nanotechnology and biotechnology has enabled revolutionary developments for drug delivery systems. Recently, drug delivery has attracted extensive research interest; applied to improve the functions of these carriers and their applications.

Objective: Active drug delivery is currently approved as an ideal approach for targeted transport in a biological entity and can cooperate with therapeutic mediums in transporting cargoes.

Results and conclusion: In this review, several active targeted cargomediated drug delivery patterns have been summarized, including molecular motors, bio-camouflaged particles, and self-propelled nanomotors. Subsequently, a series of active targeted carriers for drug delivery were introduced, and their ability for targeted binding was discussed. Furthermore, the mechanism of active targeted transport was exposited in detail, and some promising works are highlighted.

Cite this article as:

Shao Jingxin, Xuan Mingjun, He Qiang*, Dai Luru*, Bioinspired Platform Conjugated Active Drug Delivery, Current Drug Targets 2018; 19 (4) . https://dx.doi.org/10.2174/1389450117666160602202850