Abstract
The chemistry of lithiated α-chloroalkylheterocycles such as α-chloroalkylbenzothiazoles, - benzotriazoles, -pyridines, -triazines, -thiazoles and -oxazolines has been reviewed. The synthetic application of this kind of chemistry for the stereoselective preparation of heteroaryl cyclopropanes, oxiranes, aziridines, alkenes and functionalised nitroarenes through a Darzens-type reaction, has been especially emphasised.
Keywords: carbenoids, haloalkyllithiums, chemistry, reagents, reactions, ring expansion, heterocyclic ring
Current Organic Chemistry
Title: Lithiated α-Chloroalkylheterocycles: Utility in Synthetic Organic Chemistry
Volume: 8 Issue: 16
Author(s): Saverio Florio, Vito Capriati and Renzo Luisi
Affiliation:
Keywords: carbenoids, haloalkyllithiums, chemistry, reagents, reactions, ring expansion, heterocyclic ring
Abstract: The chemistry of lithiated α-chloroalkylheterocycles such as α-chloroalkylbenzothiazoles, - benzotriazoles, -pyridines, -triazines, -thiazoles and -oxazolines has been reviewed. The synthetic application of this kind of chemistry for the stereoselective preparation of heteroaryl cyclopropanes, oxiranes, aziridines, alkenes and functionalised nitroarenes through a Darzens-type reaction, has been especially emphasised.
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Cite this article as:
Florio Saverio, Capriati Vito and Luisi Renzo, Lithiated α-Chloroalkylheterocycles: Utility in Synthetic Organic Chemistry, Current Organic Chemistry 2004; 8 (16) . https://dx.doi.org/10.2174/1385272043369719
DOI https://dx.doi.org/10.2174/1385272043369719 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |

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