摘要
老年痴呆症患者常见痴呆的行为和精神症状(BPSD)。BPSD对病人和照顾者有着重大的影响。关于BPSD治疗的药理学方法可用的文献是稀少的,有时呈现不一致的结果。没有FDA批准用于BPSD治疗的药物,老年人群痴呆可用药物的使用与明显的副作用有关。此文概述了BPSD的评估,探讨了药物管理的总则,并审查了目前非药物和药物治疗策略以及相关风险的证据。
关键词: 阿尔茨海默病,焦虑,痴呆的行为和心理症状,老年痴呆症,抑郁,治疗。
Current Alzheimer Research
Title:The Treatment of Behavioral and Psychological Symptoms of Dementia: Weighing Benefits and Risks
Volume: 13 Issue: 10
Author(s): Kristina F. Zdanys, André F. Carvalho, Rajesh R. Tampi, David C. Steffens
Affiliation:
关键词: 阿尔茨海默病,焦虑,痴呆的行为和心理症状,老年痴呆症,抑郁,治疗。
摘要: Behavioral and psychological symptoms of dementia (BPSD) are common among patients with dementia. BPSD have significant implications on outcomes for patients and caregivers. Available literature for pharmacological approaches to BPSD is sparse and at times inconsistent. There are no FDA-approved medications for the management of BPSD, and the use of available medications is associated with significant adverse effects among aged populations with dementia. This review outlines the assessment of BPSD, discusses general principles of management, and examines current evidence for non-pharmacologic and pharmacologic treatment strategies as well as associated risks.
Export Options
About this article
Cite this article as:
Kristina F. Zdanys, André F. Carvalho, Rajesh R. Tampi, David C. Steffens , The Treatment of Behavioral and Psychological Symptoms of Dementia: Weighing Benefits and Risks, Current Alzheimer Research 2016; 13 (10) . https://dx.doi.org/10.2174/1567205013666160510121633
DOI https://dx.doi.org/10.2174/1567205013666160510121633 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
![](/images/wayfinder.jpg)
- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Glutamate Carboxypeptidase II in Diagnosis and Treatment of Neurologic Disorders and Prostate Cancer
Current Medicinal Chemistry Chemistry, Biological Properties and SAR Analysis of Quinoxalinones
Mini-Reviews in Medicinal Chemistry Natural Polymeric Nanoparticles for Brain-Targeting: Implications on Drug and Gene Delivery
Current Pharmaceutical Design Alzheimers Disease and Immunotherapy
Current Alzheimer Research A Healthy Gut for a Healthy Brain: Preclinical, Clinical and Regulatory Aspects
Current Neuropharmacology Exploring Molecular Approaches in Amyotrophic Lateral Sclerosis: Drug Targets from Clinical and Pre-Clinical Findings
Current Molecular Pharmacology Recent Developments in the Separation of Low Molecular Weight Heparin Anticoagulants
Current Medicinal Chemistry The Interrelationship Between Disease and Ageing and the Implications for Longevity
Current Aging Science Gut Permeability and Microbiota in Parkinson’s Disease: Role of Depression, Tryptophan Catabolites, Oxidative and Nitrosative Stress and Melatonergic Pathways
Current Pharmaceutical Design Excitotoxicity as a Target Against Neurodegenerative Processes
Current Pharmaceutical Design Molecular Mechanisms, Emerging Etiological Insights and Models to Test Potential Therapeutic Interventions in Alzheimers Disease
Current Alzheimer Research Brain Information Sharing During Visual Short-Term Memory Binding Yields a Memory Biomarker for Familial Alzheimer's Disease
Current Alzheimer Research The Urokinase Receptor in the Central Nervous System
CNS & Neurological Disorders - Drug Targets Sculpted Amphiphilic Liposomal Particles for Modifiable Medicinal Applications
Current Drug Discovery Technologies Virgin Olive Oil and Hypertension
Current Vascular Pharmacology Lipid Biomarkers in Alzheimer's Disease
Current Alzheimer Research Meta-Analysis of the Effectiveness and Safety of Prophylactic Use of Nimodipine in Patients with an Aneurysmal Subarachnoid Haemorrhage
CNS & Neurological Disorders - Drug Targets From Pharmacotherapy to Pathophysiology: Emerging Mechanisms of Apolipoprotein D in Psychiatric Disorders
Current Molecular Medicine Neuroprotective Mechanisms as Treatment Strategy in Alzheimers disease
Current Medicinal Chemistry - Central Nervous System Agents The Application of Minerals in Managing Alcohol Hangover: A Preliminary Review
Current Drug Abuse Reviews