摘要
多糖的化学修饰与多糖在主链或支链上功能基或者一些特殊结构的优化方法的使用有关。这些化学方法包括硫酸盐化作用、磷酸化、酯化、碳甲基化等。因此,多糖的空间结构、理化性质变化能够加强多糖等的生物活性、免疫调节、抗真菌、抗肿瘤和抗氧化等活性。
关键词: 抗氧化活性;抗肿瘤活性;抗真菌活性;生物活性;化学修饰;增强免疫;多糖
图形摘要
Current Drug Targets
Title:Chemical Modifications and Biological Activities of Polysaccharides
Volume: 17 Issue: 15
Author(s): Gangliang Huang, Xin Chen, Hualiang Huang
Affiliation:
关键词: 抗氧化活性;抗肿瘤活性;抗真菌活性;生物活性;化学修饰;增强免疫;多糖
摘要: The chemical modifications of polysaccharides involve the use of chemical methods to modify some special structures or functional groups of polysaccharides on the main chains or side chains. The chemical methods include sulfation, phosphorylation, acetylation, carboxymethylation etc. Therefore, spatial structures, and physical and chemical properties of polysaccharides change, which enhance the biological activities of polysaccharides, e.g., immune regulation, antivirus, anti-tumor, anti-oxidation, etc.
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Cite this article as:
Gangliang Huang, Xin Chen, Hualiang Huang , Chemical Modifications and Biological Activities of Polysaccharides, Current Drug Targets 2016; 17 (15) . https://dx.doi.org/10.2174/1389450117666160502151004
DOI https://dx.doi.org/10.2174/1389450117666160502151004 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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