天然AMPK活化剂：代谢综合征治疗和治疗的替代方法

Title:Natural AMPK Activators: An Alternative Approach for the Treatment and Management of Metabolic Syndrome

Volume: 24 Issue: 10

关键词: 心血管疾病，糖尿病，肥胖症，代谢综合征，转录因子，植物成分。

摘要: This review covers recent discoveries of phytoconstituents, herbal extracts and some semi-synthetic compounds for treating metabolic syndrome with AMPK activation as one of their mechanisms of action. Recent researches have demonstrated AMPK activation to ameliorate multiple components of metabolic syndrome by regulating a balance between anabolic and catabolic cellular reactions. The review attempts to delineate the AMPK activation by natural agents from the perspective of its functional consequences on enzymes, transcription factors and signaling molecules and also on other potential factors contributing in the amelioration of metabolic syndrome.

Cite this article as:

Natural AMPK Activators: An Alternative Approach for the Treatment and Management of Metabolic Syndrome, Current Medicinal Chemistry 2017; 24 (10) . https://dx.doi.org/10.2174/0929867323666160406120814