Title:Morin: A Promising Natural Drug
Volume: 23
Issue: 8
Author(s): Anna Caselli, Paolo Cirri, Alice Santi and Paolo Paoli
Affiliation:
关键词:
桑色素、黄酮、多酚、天然药物、抗氧化、抗糖尿病、抗炎。
摘要: Morin is a natural polyphenol, originally isolated from members of the Moraceae
family that can be extracted from leaves, fruits, stems and branches of numerous plants. Several
evidence have demonstrated that Morin could have a beneficial effect on several human
diseases. In fact, Morin exerts antioxidant, antidiabetic, anti-inflammatory, antitumoral, antihypertensive,
antibacterial, hypouricemic, and neuroprotective effects, by modulating the activity
of many enzymes. In some cases, Morin shows a systemic protective action, reducing
negative side effects of several drugs, without interfering with their functions. In addition, in vitro and in vivo
studies demonstrated that Morin exhibits very low toxicity levels and its chronic administration is well tolerated.
All these findings suggest that Morin could be used, either alone or in combination with other drugs, to
prevent many human pathologies.