Bis(iminophosphoranes) as Useful Building Blocks for the Preparation of Complex Polyaza Ring Systems

Title: Bis(iminophosphoranes) as Useful Building Blocks for the Preparation of Complex Polyaza Ring Systems

Volume: 8 Issue: 9

Author(s): Antonio Arques and Pedro Molina

Affiliation:

Keywords: wittig-type reaction, bis(iminophosphoranes), diels-alder cycloaddition., iminophosphoranes

Abstract: Several methodologies based on the aza Wittig-type reaction of bis(iminophosphoranes) have been used for the preparation of a wide variety of nitrogen-containing heterocyclic ring systems. The resulting aza Wittig products, functionalized heterocumulenes, undergo cyclization either by electrocyclic ring-closure, intramolecular amination, [2+2] cycloaddition or intramolecular Diels-Alder cycloaddition. The synthetic utility of bis(iminophosphoranes) when the two iminophosphoranes groups show different reactivity (N-iminophosphorane > C-vinyliminophosphorane > C-aryliminophosphorane) toward the same functionality is also reported.

Cite this article as:

Arques Antonio and Molina Pedro, Bis(iminophosphoranes) as Useful Building Blocks for the Preparation of Complex Polyaza Ring Systems, Current Organic Chemistry 2004; 8 (9) . https://dx.doi.org/10.2174/1385272043370546