摘要
新的T细胞治疗靶向白血病的发展促进了这种方法对恶性血液病的翻译。不同的方法制造白血病特异性T细胞的发展,以及额外的措施,以增加这种疗法的安全性。这是一个扩展的T细胞治疗的概述,重点是如何改良制造战略,以及在哪个研究拔头。
关键词: 细胞治疗,白血病抗原,体外扩增T细胞。
图形摘要
Current Drug Targets
Title:Adoptive Immunotherapy For Leukemia With Ex vivo Expanded T Cells
Volume: 18 Issue: 3
Author(s): Conrad R.Y. Cruz, Catherine M. Bollard.
Affiliation:
关键词: 细胞治疗,白血病抗原,体外扩增T细胞。
摘要: The development of novel T cell therapies to target leukemia has facilitated the translation of this approach for hematologic malignancies. Different methods of manufacturing leukemia-specific T cells have evolved, along with additional measures to increase the safety of this therapy. This is an overview of expanded T cell therapeutics with a focus on how the manufacturing strategies have been refined, and where the research is heading.
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Cite this article as:
Conrad R.Y. Cruz, Catherine M. Bollard. , Adoptive Immunotherapy For Leukemia With Ex vivo Expanded T Cells, Current Drug Targets 2017; 18 (3) . https://dx.doi.org/10.2174/1389450117666160209143529
DOI https://dx.doi.org/10.2174/1389450117666160209143529 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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