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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Synthesis and Applications of Glyconanoparticles

Author(s): Baoyong Liu, Xiaowei Lu, Hong Ruan, Jiwei Cui and Hongguang Li

Volume 20, Issue 14, 2016

Page: [1502 - 1511] Pages: 10

DOI: 10.2174/1385272820666151207194453

Price: $65

Abstract

Glyconanoparticles are the subject of numerous literatures and are emerging for applications in biomedicine, glycoscience, and material science due to their unique properties. They are hybrid materials each of which contains a nanoparticle core surrounded by a carbohydrate shell. The core can be metallic, magnetic, and/or photoluminescent, while the shell may be composed of mono-, di-, oligo- and/or poly-saccharides. Sugars are attached to the surface of the nanoparticles through covalent or non-covalent interaction. Here, we give a brief summary of the synthetic methodologies adopted in the preparation of different types of glyconanoparticles, which can be utilized in various applications including catalysis, drug delivery, vaccine, imaging and study of carbohydrate-lectin interactions.

Keywords: Glyconanoparticles, methodologies, carbohydrate-lectin interactions, biomedicine.

Graphical Abstract


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