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Current Aging Science

Editor-in-Chief

ISSN (Print): 1874-6098
ISSN (Online): 1874-6128

Age-Related Sleep Changes and its Implication in Neurodegenerative Diseases

Author(s): Elena A. Lyashenko, Michael G. Poluektov, Oleg S. Levin and Polina V. Pchelina

Volume 9, Issue 1, 2016

Page: [26 - 33] Pages: 8

DOI: 10.2174/1874609809666151130220219

Price: $65

Abstract

In the article authors discuss the current data on sleep changes with aging focusing on the influence of age-related degenerative changes in orexin-containing and pacemaker brain areas. Pathophysiological mechanisms of sleep disturbances in Parkinson’s and Alzheimer’s diseases have much in common with normal age neurophysiological changes. Maintenance of the sleep-promoting systems function could positively modify the course of these diseases.

Keywords: Age, Alzheimer’s disease, Parkinson’s disease, sleep, orexins, sleep disorders.


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