摘要
糖尿病在全球范围内正在蔓延。 已经发现许多饮食化合物对包括糖尿病在内的不同病理发挥健康有益作用。 大多数生物活性化合物已被鉴定在水果和蔬菜中,其作用机制在体外和体内都被探讨。 特别地,对多酚,特别是分子的特定子集(即花青素)给予了极大的兴趣。 几条证据表明,花青素通过诱导一些生物活性对人体健康有积极的影响。 该评论将概述饮食花青素对预防和治疗2型糖尿病的影响。 具体来说,将介绍体外和体内研究。 本文还回顾了花青素抗糖尿病活性的潜在临床影响,并概述了使用花青素进行糖尿病治疗的主要挑战。
关键词: 花青素,花青素,抗氧化活性,花青素,糖尿病,酶机制,非酶促机制。
图形摘要
Current Drug Targets
Title:Possible Effects of Dietary Anthocyanins on Diabetes and Insulin Resistance
Volume: 18 Issue: 6
关键词: 花青素,花青素,抗氧化活性,花青素,糖尿病,酶机制,非酶促机制。
摘要: Diabetes is reaching epidemic proportions worldwide. Many dietary compounds have been found to exert health beneficial effects against different pathologies including diabetes. Most bioactive compounds have been identified in fruits and vegetables and their mechanisms of action explored both in vitro and in vivo. In particular, great interest has been given to polyphenols and especially to a specific subset of molecules, i.e. anthocyanins. Several lines of evidence suggest that anthocyanins have positive effects on human health by inducing a number of biological activities. This review will give an overview on the influence of dietary anthocyanins on preventing and managing type 2 diabetes. In particular, in vitro and in vivo studies will be presented. The article also reviews the potential clinical impact of the antidiabetic activity of anthocyanins and outlines the major challenges of using anthocyanins for diabetes treatment.
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Cite this article as:
Possible Effects of Dietary Anthocyanins on Diabetes and Insulin Resistance, Current Drug Targets 2017; 18 (6) . https://dx.doi.org/10.2174/1389450116666151001105230
DOI https://dx.doi.org/10.2174/1389450116666151001105230 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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