Extracellular Vesicles as Novel Delivery Tools for Cancer Treatment

Title:Extracellular Vesicles as Novel Delivery Tools for Cancer Treatment

Volume: 16 Issue: 1

Author(s): Erdogan Pekcan Erkan and Okay Saydam

Affiliation:

Keywords: Cancer, delivery, extracellular vesicles, therapeutics.

Abstract: Extracellular vesicles (EVs) are different types of membrane-derived vesicles that originate from the endosomal pathway or the plasma membrane. These vesicles are used as "carriers" in intercellular communication, and are responsible for the transfer of biological cargo (lipids, proteins, RNA species, and DNA) between different cells. Despite the shortcomings in our knowledge of EV biology, attempts to employ EVs as natural delivery tools for therapeutic purposes have been partly successful in different settings. In this review, we highlight this unique potential of EVs, and discuss previous examples and future scenarios.

Cite this article as:

Erkan Pekcan Erdogan and Saydam Okay, Extracellular Vesicles as Novel Delivery Tools for Cancer Treatment, Current Cancer Drug Targets 2016; 16 (1) . https://dx.doi.org/10.2174/1568009615666150923115439