Recent Advances in the Asymmetric Claisen Rearrangement Promoted by Chiral Organometallic Lewis Acids or Organic Bronsted-Lowry Acids

Title:Recent Advances in the Asymmetric Claisen Rearrangement Promoted by Chiral Organometallic Lewis Acids or Organic Bronsted-Lowry Acids

Volume: 12 Issue: 6

Author(s): Tiago Costa Alves Fontoura Rodrigues, Wender Alves Silva and Angelo Henrique Lira Machado

Affiliation:

Keywords: [3, 3] sigmatropic, organocatalysis, chiral Lewis acids, claisen rearrangement, asymmetric rearrangement, catalysis.

Abstract: The Claisen rearrangement, an important C–C bond forming reaction, has been used enormously for many decades in the synthesis of important class of compounds. This review covers developments in this rearrangement since 2008, discusses important aspects about the asymmetric Claisen rearrangement catalyzed by chiral organometallic Lewis acids or organic Brønsted-Lowry acids.

Cite this article as:

Fontoura Rodrigues Costa Alves Tiago, Silva Alves Wender and Lira Machado Henrique Angelo, Recent Advances in the Asymmetric Claisen Rearrangement Promoted by Chiral Organometallic Lewis Acids or Organic Bronsted-Lowry Acids, Current Organic Synthesis 2015; 12 (6) . https://dx.doi.org/10.2174/157017941206150828112854