Biopolymer-Based Delivery Systems: Challenges and Opportunities

Title:Biopolymer-Based Delivery Systems: Challenges and Opportunities

Volume: 16 Issue: 9

Author(s): Iris J. Joye and D. Julian McClements

Affiliation:

Keywords: Proteins, Polysaccharides, Nanoparticles, Microparticles, Fibers, Films, Delivery systems, Controlled release.

Abstract: Biopolymer-based nanostructures or microstructures can be fabricated with different compositions, structures, and properties so that colloidal delivery systems can be tailored for specific applications. These structures can be assembled using various approaches, including electrospinning, coacervation, nanoprecipitation, injection, layer-by-layer deposition, and/or gelation. A major application of biopolymer-based particles is to encapsulate, protect, and release active molecules in the agricultural, food, supplements, personal care, and pharmaceutical sectors. The inherent variability and complexity of biopolymers (proteins and polysaccharides) often makes it challenging to produce particles with well-defined physicochemical and functional attributes. In this review, we discuss the properties of biopolymers, common particle fabrication methods, and some of the major challenges and opportunities associated with developing biopolymer-based particles for application as food-grade delivery systems.

Cite this article as:

Joye J. Iris and McClements Julian D., Biopolymer-Based Delivery Systems: Challenges and Opportunities, Current Topics in Medicinal Chemistry 2016; 16 (9) . https://dx.doi.org/10.2174/1568026615666150825143130