Abstract
Nanotechnology has shown great promise in health care offering numerous possibilities to significantly improve diagnosis of many dreadful diseases including Tuberculosis (TB). Nanomedicine has made the current drug regimen more effective against diseases particularly TB with attributes like sustained release, increased half life, higher drug concentrations at target sites, reduced toxicity and lesser side effects. However because of the severity of the disease, there is a strong urge to develop better approaches with some concomitant regimens using nano-particles to diagnose, treat and manage TB patients. The current review highlights some of the evolving strategies in the field of nanomedicine particularly drug delivery offering promising alternative for the current TB regimens. The study also emphasizes upon the need to design more effective nanocarriers which are highly specific, biocompatible and biodegradable as well.
Keywords: Nanomedicine, TB, nanocarriers, drugs, drug regimen.
Current Drug Targets
Title:Nano-Based Anti-Tubercular Drug Delivery and Therapeutic Interventions in Tuberculosis
Volume: 18 Issue: 1
Author(s): Rohit Sharma, Amanpreet Kaur, A. K. Sharma, Neeraj Dilbaghi and Anil K. Sharma
Affiliation:
Keywords: Nanomedicine, TB, nanocarriers, drugs, drug regimen.
Abstract: Nanotechnology has shown great promise in health care offering numerous possibilities to significantly improve diagnosis of many dreadful diseases including Tuberculosis (TB). Nanomedicine has made the current drug regimen more effective against diseases particularly TB with attributes like sustained release, increased half life, higher drug concentrations at target sites, reduced toxicity and lesser side effects. However because of the severity of the disease, there is a strong urge to develop better approaches with some concomitant regimens using nano-particles to diagnose, treat and manage TB patients. The current review highlights some of the evolving strategies in the field of nanomedicine particularly drug delivery offering promising alternative for the current TB regimens. The study also emphasizes upon the need to design more effective nanocarriers which are highly specific, biocompatible and biodegradable as well.
Export Options
About this article
Cite this article as:
Sharma Rohit, Kaur Amanpreet, Sharma K. A., Dilbaghi Neeraj and Sharma K. Anil, Nano-Based Anti-Tubercular Drug Delivery and Therapeutic Interventions in Tuberculosis, Current Drug Targets 2017; 18 (1) . https://dx.doi.org/10.2174/1389450116666150804110238
DOI https://dx.doi.org/10.2174/1389450116666150804110238 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Alterations in the Vascular Reactivity of Aorta in the Early and Late Phase of Adjuvant-Induced Arthritis in Rat
Vascular Disease Prevention (Discontinued) Increase of R-/S-Methadone Enantiomer Concentration Ratio in Serum of Patients Treated with Either Nevirapine or Efavirenz
Drug Metabolism Letters Molecular and Biochemical Features of the Mitochondrial Enzyme Ornithine Transcarbamylase: A Possible New Role as a Signaling Factor
Current Medicinal Chemistry Different Methods for Molecular and Rapid Detection of Human Novel Coronavirus
Current Pharmaceutical Design Interactions Between Proteins and Platinum-Containing Anti-Cancer Drugs
Mini-Reviews in Medicinal Chemistry New Strategies and Paradigm for Drug Target Discovery: A Special Focus on Infectious Diseases Tuberculosis, Malaria, Leishmaniasis, Trypanosomiasis and Gastritis
Infectious Disorders - Drug Targets Pulmonary Complications in Diabetes Mellitus: The Role of Glycemic Control
Current Drug Targets - Inflammation & Allergy HLA and TCR Recognition of Medications in Severe Cutaneous Adverse Reactions
Current Immunology Reviews (Discontinued) Artificial Intelligence Approaches for Rational Drug Design and Discovery
Current Pharmaceutical Design What Strategies to Boost Production of Affordable Fixed-Dose Anti-Retroviral Drug Combinations for Children in the Developing World?
Current HIV Research The Common Mycobacterial Antigens and their Importance in the Treatment of Disease
Current Pharmaceutical Design Microwave-Enhanced α-Arylation of a Protected Glycine in Water:Evaluation of 3-Phenylglycine Derivatives as Inhibitors of the Tuberculosis Enzyme, Glutamine Synthetase
Combinatorial Chemistry & High Throughput Screening Transbronchial Needle Aspiration (TBNA): Past Present and Future
Current Respiratory Medicine Reviews Hybrid Drugs as Potential Combatants Against Drug-Resistant Microbes: A Review
Current Topics in Medicinal Chemistry Quality-by-design Enabled Chitosan Nanoparticles for Antitubercular Therapy: Formulation, Statistical Optimization, and <i>In Vitro</i> Characterization
Current Drug Therapy HPLC-DAD-Q-TOF/MS-Based Screening and Analysis of the Multiple Absorbed Bioactive Components in Rat Serum after Oral Administration of Xiexin Tang
Current Pharmaceutical Analysis Bacterial Fatty Acid Synthesis: Effect of Tween 80 on Antibiotic Potency Against Streptococcus Agalactiae and Methicillin-Resistant Staphylococcus Aureus
Anti-Infective Agents Noninvasive Assessment of Cytokines in Occupational Respiratory Diseases
Recent Patents on Inflammation & Allergy Drug Discovery Synthetic Polyacrylate Polymers as Particulate Intranasal Vaccine Delivery Systems for the Induction of Mucosal Immune Response
Current Drug Delivery Chelating Agents for Metal Intoxication
Current Medicinal Chemistry