Abstract
IBD significantly affects the young population around the globe as the statistical reports worldwide showing the threatening growth in the IBD individuals and patients. The etiology and pathophysiology of the IBD are unclear and the causes of disease are also multifactorial. Identification, maintenance and management of the disease is a challenging aspect. This review focuses on various modern concepts revealed in the treatment of IBD. The drug therapies such as aminosalicylates, Immunomodulators, probiotics, antibiotics are used in the treatment of IBD but the choice of the drug and the combination of the drugs play a crucial role in the successful management of IBD. The various nano drug delivery systems are under extensive research throughout the world since these drug delivery systems are found successful in the treatment of IBD due to their nanosize and targeting to the inflamed sites. In the past one decade, there were several patents that were registered and approved in IBD related issues and the use of drug delivery system in the treatment of IBD. In this article various patents were consolidated in areas such as IBD related issues and nano drug deliveries in the treatment of IBD. The industrial concept and status of drug delivery system are also discussed briefly. Other important factors such as natural remedies, microscopic colitis, upcoming drugs and treatment methods related information are also critically presented in this article.
Keywords: Drug therapies, IBD, industrial concepts, nano drug delivery, patents, treatment.
Graphical Abstract
38