Abstract
The analytical determination of organic structures is a fundamental need in environmental, food and medicinal chemistry, and the chemistry of pesticide compounds is closely involved in this determination because of the environmental and biological transformations that can occur to these molecules. Degradation products often possess higher toxicity than parent substances but unknown structures, and aqueous milieu produce hard-to-solve instrumental problems. The need to analyze low concentrations in polar solutions means that methods in which liquid chromatography is hyphenated to mass spectrometry have a large playing field, which combines trace determination and structural elucidation. An important area of study comprises degradation-simulating models, such as titanium dioxide mediated photocatalytic attacks on different organic structures. HPLC-mass spectrometric studies on pesticides, their metabolites and their degradation products are reviewed.
Keywords: germicides, organophosphate, pesticide classes, liquid chromatography, chemical descriptors, chromatographic migration, organic modifiers, ion pair (ip), lc detector, thermospray (tsp)
Current Organic Chemistry
Title: Liquid Chromatography Tandem Mass Spectrometry as a Tool to Investigate Pesticides and Their Degradation Products
Volume: 9 Issue: 9
Author(s): Claudio Medana, Paola Calza, Claudio Baiocchi and Ezio Pelizzetti
Affiliation:
Keywords: germicides, organophosphate, pesticide classes, liquid chromatography, chemical descriptors, chromatographic migration, organic modifiers, ion pair (ip), lc detector, thermospray (tsp)
Abstract: The analytical determination of organic structures is a fundamental need in environmental, food and medicinal chemistry, and the chemistry of pesticide compounds is closely involved in this determination because of the environmental and biological transformations that can occur to these molecules. Degradation products often possess higher toxicity than parent substances but unknown structures, and aqueous milieu produce hard-to-solve instrumental problems. The need to analyze low concentrations in polar solutions means that methods in which liquid chromatography is hyphenated to mass spectrometry have a large playing field, which combines trace determination and structural elucidation. An important area of study comprises degradation-simulating models, such as titanium dioxide mediated photocatalytic attacks on different organic structures. HPLC-mass spectrometric studies on pesticides, their metabolites and their degradation products are reviewed.
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Cite this article as:
Medana Claudio, Calza Paola, Baiocchi Claudio and Pelizzetti Ezio, Liquid Chromatography Tandem Mass Spectrometry as a Tool to Investigate Pesticides and Their Degradation Products, Current Organic Chemistry 2005; 9 (9) . https://dx.doi.org/10.2174/1385272054038255
DOI https://dx.doi.org/10.2174/1385272054038255 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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