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Current Drug Targets

Editor-in-Chief

ISSN (Print): 1389-4501
ISSN (Online): 1873-5592

Stem Cell Therapy for Myelin Diseases

Author(s): Tamir Ben-Hur, Ofira Einstein and Jeff W.M. Bulte

Volume 6, Issue 1, 2005

Page: [3 - 19] Pages: 17

DOI: 10.2174/1389450053345000

Price: $65

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Abstract

Advances in cell biology have encouraged the hope that stem cell-based therapy can be used to heal central nervous system (CNS) diseases. Here, we will review the potential application of neural cell transplantation for the treatment of multiple sclerosis (MS) and other demyelinating disorders, mention some problematic issues that still face this therapeutic approach, and describe novel noninvasive methods for in vivo tracking of transplanted cells.

Keywords: inflammatory disease, experimental autoimmune encephalomyelitis, immunosuppressive, plp gene, picornavirus, ependymal cells


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