Abstract
The ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC/Q-TOF-MS) technique is a new approach in the chromatographic separations and has been successfully employed for fast, high resolution separations with required sensitivity. The TOF-MS is helpful in the structure elucidation and identification of fragmentation patterns of the compounds. This review provides the brief introduction and applications of UHPLC/Q-TOF-MS with examples of some of the most advanced work in the pharmaceutical analysis.
Keywords: UHPLC/Q-TOF-MS, applications, identification, determination, pharmaceutical analysis.
Graphical Abstract
Letters in Organic Chemistry
Title:UHPLC/Q-TOF-MS Technique: Introduction and Applications
Volume: 12 Issue: 6
Author(s): Hamid Khan and Javed Ali
Affiliation:
Keywords: UHPLC/Q-TOF-MS, applications, identification, determination, pharmaceutical analysis.
Abstract: The ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC/Q-TOF-MS) technique is a new approach in the chromatographic separations and has been successfully employed for fast, high resolution separations with required sensitivity. The TOF-MS is helpful in the structure elucidation and identification of fragmentation patterns of the compounds. This review provides the brief introduction and applications of UHPLC/Q-TOF-MS with examples of some of the most advanced work in the pharmaceutical analysis.
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Cite this article as:
Khan Hamid and Ali Javed, UHPLC/Q-TOF-MS Technique: Introduction and Applications, Letters in Organic Chemistry 2015; 12 (6) . https://dx.doi.org/10.2174/1570178612666150331204147
DOI https://dx.doi.org/10.2174/1570178612666150331204147 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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