A Novel Multi-functional Fluorescent Probe for Cu2+, Fe3+ and Ag+ Based on a Pyrimidine Thiourea Derivative

Title:A Novel Multi-functional Fluorescent Probe for Cu2+, Fe3+ and Ag+ Based on a Pyrimidine Thiourea Derivative

Volume: 11 Issue: 4

Author(s): Hassan H. Hammud, Mohammad H. El-Dakdouki, Nada Sonji, Ghassan Sonji and Kamal H. Bouhadir

Affiliation:

Keywords: 5, 6-diamino-1, 3-dimethyluracil, fluorescent probe, silver, ferric, cupric ion, sensor.

Abstract: A multi-functional “turn-off” fluorescent probe, N-[[(6-Amino-1,2,3,4-tetrahydro-1,3- dimethyl-2,4-dioxo-5-pyrimidinyl)amino]thioxomethyl]- benzamide, was synthesized and characterized. The probe showed high sensitivity and selectivity towards copper(II), iron(III) and silver(I) ions via quenching of its fluorescence. The detection limits were found to be 4.0 – 16.0 ppb for the assayed cations. The thiourea linked uracil fluorescent probe is proved to be sensitive, selective, applicable in real samples and promise for practical applications.

Cite this article as:

Hammud H. Hassan, El-Dakdouki H. Mohammad, Sonji Nada, Sonji Ghassan and Bouhadir H. Kamal, A Novel Multi-functional Fluorescent Probe for Cu2+, Fe3+ and Ag+ Based on a Pyrimidine Thiourea Derivative, Current Analytical Chemistry 2015; 11 (4) . https://dx.doi.org/10.2174/1573411011666150324231041