Facile One-Pot Synthesis of Oxo-Xanthenes under Microwave Irradiation

Title:Facile One-Pot Synthesis of Oxo-Xanthenes under Microwave Irradiation

Volume: 2 Issue: 1

Author(s): Amreeta Preetam, Davinder Prasad, Jatin K. Sharma and Mahendra Nath

Affiliation:

Keywords: 9-Aryl-3, 4, 5, 6, 7, 9-hexahydro-1H-xanthene-1, 8(2H)-diones, 9-substituted-2, 3, 4, 9-tetrahydro-1H-xanthen-1-ones, 12-aryl-8, 9, 10, 12-tetrahydrobenzo[a]-xanthene-11-ones, Brønsted acid surfactant combined catalyst, eco-friendly protocol, microwave-assisted synthesis, mild process, multi-component reactions, one-pot methodology, oxo-xanthenes, p-dodecylbenzenesulfonic acid, single crystal XRD data, solvent-free conditions.

Abstract: A convenient diversity oriented synthetic procedure for the construction of various oxo-xanthenes such as 12- aryl-8,9,10,12-tetrahydrobenzo[a]-xanthene-11-ones, 9-aryl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-diones and 9- substituted-2,3,4,9-tetrahydro-1H-xanthen-1-ones has been developed by using p-dodecylbenzenesulfonic acid as an efficient Brønsted acid catalyst under solvent-free microwave conditions. The present methodology is found to be operationally simple and demonstrates many advantages including shorter reaction times, easy purification steps and good to excellent yields of the target products.

Cite this article as:

Preetam Amreeta, Prasad Davinder, Sharma K. Jatin and Nath Mahendra, Facile One-Pot Synthesis of Oxo-Xanthenes under Microwave Irradiation, Current Microwave Chemistry 2015; 2 (1) . https://dx.doi.org/10.2174/221333560201150212102647