Spin Trapping: An Essential Tool for the Study of Diseases Caused by Oxidative Stress

Title:Spin Trapping: An Essential Tool for the Study of Diseases Caused by Oxidative Stress

Volume: 15 Issue: 5

Author(s): German Barriga-Gonzalez, Claudio Olea-Azar, Maria C. Zuniga-Lopez, Christian Folch-Cano, Benjamin Aguilera-Venegas, Williams Porcal, Mercedes Gonzalez and Hugo Cerecetto

Affiliation:

Keywords: DMPO, EPR, ESR, Human diseases, Immuno-spin trapping, Oxidative stress, PBN, Spin traps.

Abstract: Electron spin resonance (ESR), called also electron paramagnetic resonance (EPR) together with the spin trapping technique, has allowed us to study and understand how free radicals are involved in various pathologies. In this review, the importance of spin trapping technique in the study of diseases such as cancer, diabetes, hypertension and parasitic diseases is discussed. In addition, advances in the use of this technique as therapeutic agents and other interesting applications as the immuno-spin trapping technique are reviewed.

Cite this article as:

Barriga-Gonzalez German, Olea-Azar Claudio, Zuniga-Lopez C. Maria, Folch-Cano Christian, Aguilera-Venegas Benjamin, Porcal Williams, Gonzalez Mercedes and Cerecetto Hugo, Spin Trapping: An Essential Tool for the Study of Diseases Caused by Oxidative Stress, Current Topics in Medicinal Chemistry 2015; 15 (5) . https://dx.doi.org/10.2174/1568026615666150206155108