A Rapid, Efficient Method for Deprotection of Oximes to Carbonyl Compounds with NaClO2 in Water

Yuan-Yuan      Yao; Xian-Liang      Zhao

doi:10.2174/157017861201150112125024

Abstract

A rapid, efficient method for deprotection of oximes to carbonyl compounds is demonstrated by using sodium chlorite (NaClO₂) in water. The protocol has been found to be applicable to a wide range of aldoximes and ketoximes with good to excellent yields of the corresponding carbonyl compounds.

Keywords: Sodium chlorite, oximes, carbonyl compounds, aqueous conditions.

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Letters in Organic Chemistry

Title:A Rapid, Efficient Method for Deprotection of Oximes to Carbonyl Compounds with NaClO₂ in Water

Volume: 12 Issue: 1

Author(s): Yuan-Yuan Yao and Xian-Liang Zhao

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Keywords: Sodium chlorite, oximes, carbonyl compounds, aqueous conditions.

Abstract: A rapid, efficient method for deprotection of oximes to carbonyl compounds is demonstrated by using sodium chlorite (NaClO₂) in water. The protocol has been found to be applicable to a wide range of aldoximes and ketoximes with good to excellent yields of the corresponding carbonyl compounds.

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Yao Yuan-Yuan and Zhao Xian-Liang, A Rapid, Efficient Method for Deprotection of Oximes to Carbonyl Compounds with NaClO₂ in Water, Letters in Organic Chemistry 2015; 12 (1) . https://dx.doi.org/10.2174/157017861201150112125024

DOI https://dx.doi.org/10.2174/157017861201150112125024	Print ISSN 1570-1786
Publisher Name Bentham Science Publisher	Online ISSN 1875-6255