Abstract
Ammonium carbamate can be used as a very effective reagent for preparation of 2,4,6- triarylpyridine derivatives from ring transformation of pyrylium salts under solvent-free conditions. The products are isolated without aqueous work-up in high purity and good yields. The microwave accelerated the reaction and renders the whole synthesis into a truly eco-friendly protocol.
Keywords: Ammonium carbamate, microwave, nucleophilic reaction, pyrylium salts, solid ammonia source, solvent-free reaction conditions, triarylpyridine.
Graphical Abstract