3个案例的报道：炎性肠病患者血栓栓塞事件的预防和治疗方案

Title:Prevention and Therapeutic Strategies of Thromboembolic Events in Patients with Inflammatory Bowel Diseases: A Report of Three Cases

Volume: 16 Issue: 3

Author(s): Marcin Wlodarczyk, Aleksandra Sobolewska, Jakub Fichna and Maria Wisniewska-Jarosinska

Affiliation:

关键词: 抗凝血剂，炎性肠病，低分子量肝素，血栓栓塞的预防，静脉血栓栓塞

摘要: Crohn’s disease and ulcerative colitis belong to a group of inflammatory bowel diseases (IBD). IBD are characterized by a chronic character of inflammatory process and overlapping immunological abnormalities, which, along with therapeutic strategies are currently available, underlie an increased risk of venous thromboembolic events (VTE). The most common sites of VTE in IBD patients are deep venous thrombosis (DVT) and pulmonary embolism (PE). These complications are particularly important in clinical practice due to a very high mortality rate. Therefore, an early diagnosis of new IBD cases and the control of inflammatory process are thought to play a crucial role in risk reduction for thromboembolic events. Despite considerable evidence supporting the association between IBD and VTE, there is still a lack of recognition of this risk, with dangerous consequences for patients. In this paper authors report three cases of VTE in IBD patients and discuss the most relevant clinical studies found in MEDLINE, Cochrane Library and EMBASE regarding its prevention and management.

Cite this article as:

Marcin Wlodarczyk, Aleksandra Sobolewska, Jakub Fichna and Maria Wisniewska-Jarosinska , Prevention and Therapeutic Strategies of Thromboembolic Events in Patients with Inflammatory Bowel Diseases: A Report of Three Cases, Current Drug Targets 2015; 16 (3) . https://dx.doi.org/10.2174/1389450115666141109213152