多聚体和纳米纤维系统的组成在组织工程学及药物给药过程中的应用

Title:Polymers and Formulation Strategies of Nanofibrous Systems for Drug Delivery Application and Tissue Engineering

Volume: 22 Issue: 5

Author(s): I. Sebe, B. Kallai-Szabo, R. Zelko and D. Szabo

Affiliation:

关键词: 给药系统，纳米和微晶纤维，多聚体，再生医学，纺织技术，组织工程学

摘要: During the last decade, the formulation of nanofibrous materials loaded with different drugs for biomedical applications has evoked considerable interest. The large specific surface area, the special micro- and macrostructure of fiber mats, the possibility for gradual release and site-specific local delivery of the active compounds lead to cytotoxicity decrease and enhancement of the therapeutic effect of drugs and implants. The present review details the different spinning techniques applied for the design of micro- and nanofibrous drug delivery systems. It furthermore deals with the use of various polymers that are capable for the formation of fiber scaffolds of various biomedical applications.

Cite this article as:

I. Sebe, B. Kallai-Szabo, R. Zelko and D. Szabo , Polymers and Formulation Strategies of Nanofibrous Systems for Drug Delivery Application and Tissue Engineering, Current Medicinal Chemistry 2015; 22 (5) . https://dx.doi.org/10.2174/0929867321666141106105502