Abstract
Among the family of nitrogen-containing heterocycles, quinoxalinone (or quinoxalin-2-one) core, characterized by pyrazin-2(1H)-one fused to benzene ring at two adjacent carbon atoms, has been frequently found in a variety of pharmacologically active compounds with biological or pharmaceutical applications. In this article, we highlighted the synthetic methods of this scaffold, as well as its derivates.
Keywords: Quinoxalinone, reaction mechanism, synthetic method.
Graphical Abstract
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