Optimization of the Preparation Condition of 2,4,5-triphenyl-1H-imidazole Over BaSO₄ Nanoparticles as Catalyst Using a Response Surface Methodology (RSM)

Title:Optimization of the Preparation Condition of 2,4,5-triphenyl-1H-imidazole Over BaSO₄ Nanoparticles as Catalyst Using a Response Surface Methodology (RSM)

Volume: 11 Issue: 1

Author(s): Ali Behmaneshfar, Majid Ghashang, Mohammad Reza Mohammad Shafiee, Ali Saffar-Teluri, Abbas Fazlinia and Hadi Esfandiari

Affiliation:

Keywords: 2, 4, 5-triphenyl-1H-imidazole, BaSO₄ nanoparticles, Box–Behnken experimental design, response surface methodology.

Abstract: A study on the application of Response Surface Methodology (RSM) for the optimization of the process parameters of the preparation of 2,4,5-triphenyl-1H-imidazole over BaSO₄ nanoparticles as catalyst was explored. A threelevel, three-factor, Box–Behnken experimental design has been employed to determine the effects of process parameters namely temperature (20-130 °C), catalyst dosage (0.01-0.5) and initial NH₄OAc concentration (2-4 mmol). The second order mathematical model was developed by regression analysis of the experimental data obtained from 30 runs. Highest yield of product and lowest time of process were obtained at the optimum conditions as: temperature (130 °C), catalyst dosage (0.5 mmol) and NH₄OAc concentration (4 mmol).

Cite this article as:

Behmaneshfar Ali, Ghashang Majid, Shafiee Reza Mohammad Mohammad, Saffar-Teluri Ali, Fazlinia Abbas and Esfandiari Hadi, Optimization of the Preparation Condition of 2,4,5-triphenyl-1H-imidazole Over BaSO₄ Nanoparticles as Catalyst Using a Response Surface Methodology (RSM), Current Nanoscience 2015; 11 (1) . https://dx.doi.org/10.2174/1573413710666140923211414