Abstract
Bio-functional microspheres (BFMs), including drug carrier microspheres, fluorescence microspheres, magnetic microspheres, immune microspheres, enzyme immobilization microspheres, solid-phase synthesis microspheres, and molecular imprinting microspheres, are core-shell microspheres containing bio-molecules and functional materials in their structures. Because of the presence of core-shell structures and spherical shapes, BFMs bear many unique functions and fascinating properties. The research on BFMs has surprisingly blossomed during recent decades. In this review, we give a systematic, balanced and comprehensive summary of the main aspects of BFMs related to their preparation and application, and propose perspectives for future developments of BFMs.
Keywords: Bio-function, enzyme immobilization, fluorescence, immunity, microspheres.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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