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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of Novel 2-(Methylthio)benzo[g][1,2,4]triazolo[1,5-a]quinazolin- 5-(4H)-one and its Derivatives

Author(s): Rashad A. Al-Salahi, Mohamed S. Marzouk, Hazem A. Ghabbour and Fun H. Kun

Volume 11, Issue 10, 2014

Page: [759 - 767] Pages: 9

DOI: 10.2174/1570178611666140813205111

Price: $65

Abstract

A novel 2-(methylthio)benzo[g][1,2,4]triazolo[1,5-a]quinazolin-5(4H)-one was synthesized employing dimethyl N-cyanoimidodithiocarbonate and 3-hydrazinyl-2-naphthoic acid as building blocks. Chemical transformation of the inherent lactam group in the target molecule provided access to a variety of heterocylic derivatives. The obtained compounds are characterized and confirmed by NMR, IR, and HREI-MS analyses.

Keywords: 3-hydrazinyl-2-naphthoic acid, cyclocondensation, dimethyl N-cyanoimidodithiocarbonate.

Graphical Abstract


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