Synthesis and Bioactivities of Novel 1,3,4-oxadiazole Derivatives Containing Pyridine Moiety

Title:Synthesis and Bioactivities of Novel 1,3,4-oxadiazole Derivatives Containing Pyridine Moiety

Volume: 11 Issue: 9

Author(s): Guo-Xiang Sun, Yan-Xia Shi, Zhao-Hui Sun, Ming-Yan Yang, Hong-Ke Wu, Jian-Quan Weng, Cheng-Xia Tan, Xing-Hai Liu, Bao-Ju Li and Yong-Gang Zhang

Affiliation:

Keywords: 1, 3, 4-oxadiazole, antifungal activity, microwave synthesis, pyridine.

Abstract: In this paper, some novel 1,3,4-oxadiazole derivatives containing 4-pyridyl group were synthesized under microwave assistant condition by multi-step reactions. The structures were characterized by ¹H NMR, MS and elemental analyses. The target compounds were evaluated for their fungicidal activities, and the results indicated that some of the title compounds displayed good antifungal activities.

Cite this article as:

Sun Guo-Xiang, Shi Yan-Xia, Sun Zhao-Hui, Yang Ming-Yan, Wu Hong-Ke, Weng Jian-Quan, Tan Cheng-Xia, Liu Xing-Hai, Li Bao-Ju and Zhang Yong-Gang, Synthesis and Bioactivities of Novel 1,3,4-oxadiazole Derivatives Containing Pyridine Moiety, Letters in Drug Design & Discovery 2014; 11 (9) . https://dx.doi.org/10.2174/1570180811666140522002929

DOI https://dx.doi.org/10.2174/1570180811666140522002929	Print ISSN 1570-1808
Publisher Name Bentham Science Publisher	Online ISSN 1875-628X