Abstract
Ytterbium triflate, Yb(OTf)3, is a versatile Lewis acid that has high catalytic activity in many organic reactions, including aldol, Michael, Mannich, Friedel-Crafts, Diels-Alder, and some other types of reactions. Less than 10 mol% of Yb(OTf)3 is normally sufficient for most organic transformations and can be recovered and re-used without loss of catalytic activity. In addition, Yb(OTf)3 is very stable and its catalyzed reactions can be carried out in both organic solvents and aqueous conditions.
Keywords: Ytterbium triflate, Catalyst, Aldol condensation, Michael addition, Mannich reaction, Friedel-crafts, Diels-alder.
Current Organic Chemistry
Title:Ytterbium Triflate: A Versatile Catalyst in Organic Synthesis
Volume: 17 Issue: 23
Author(s): Lang-Jun Zhang, He-Lin Lu, Zong-Wen Wu and Yun-Sheng Huang
Affiliation:
Keywords: Ytterbium triflate, Catalyst, Aldol condensation, Michael addition, Mannich reaction, Friedel-crafts, Diels-alder.
Abstract: Ytterbium triflate, Yb(OTf)3, is a versatile Lewis acid that has high catalytic activity in many organic reactions, including aldol, Michael, Mannich, Friedel-Crafts, Diels-Alder, and some other types of reactions. Less than 10 mol% of Yb(OTf)3 is normally sufficient for most organic transformations and can be recovered and re-used without loss of catalytic activity. In addition, Yb(OTf)3 is very stable and its catalyzed reactions can be carried out in both organic solvents and aqueous conditions.
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Cite this article as:
Zhang Lang-Jun, Lu He-Lin, Wu Zong-Wen and Huang Yun-Sheng, Ytterbium Triflate: A Versatile Catalyst in Organic Synthesis, Current Organic Chemistry 2013; 17 (23) . https://dx.doi.org/10.2174/138527281723131218135830
DOI https://dx.doi.org/10.2174/138527281723131218135830 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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