Efficient Synthesis of 2,4,5-Triaryl-1H-Imidazoles from Aromatic Aldehydes with HMDS Catalyzed by N-Bromosaccharin (NBSa)

Alireza      Sedrpoushan; Zinab      Joshani; Leila      Fatollahi

doi:10.2174/15701786113106660091

Abstract

A one-pot efficient procedure for the synthesis of 2, 4, 5-triaryl-1H-imidazole derivatives by the reactions of hexamethyldisilazane and arylaldehydes in the presence of N-bromosaccharin (NBSa) is studied. This new method offers several advantages, such as excellent yields, easy workup, short reaction times, and simple procedure.

Keywords: 2, 4, 5-triaryl-1H-imidazole, hexamethyldisilazane, N-Bromosaccharin (NBSa).

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Letters in Organic Chemistry

Title:Efficient Synthesis of 2,4,5-Triaryl-1H-Imidazoles from Aromatic Aldehydes with HMDS Catalyzed by N-Bromosaccharin (NBSa)

Volume: 11 Issue: 4

Author(s): Alireza Sedrpoushan, Zinab Joshani and Leila Fatollahi

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Keywords: 2, 4, 5-triaryl-1H-imidazole, hexamethyldisilazane, N-Bromosaccharin (NBSa).

Abstract: A one-pot efficient procedure for the synthesis of 2, 4, 5-triaryl-1H-imidazole derivatives by the reactions of hexamethyldisilazane and arylaldehydes in the presence of N-bromosaccharin (NBSa) is studied. This new method offers several advantages, such as excellent yields, easy workup, short reaction times, and simple procedure.

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Sedrpoushan Alireza, Joshani Zinab and Fatollahi Leila, Efficient Synthesis of 2,4,5-Triaryl-1H-Imidazoles from Aromatic Aldehydes with HMDS Catalyzed by N-Bromosaccharin (NBSa), Letters in Organic Chemistry 2014; 11 (4) . https://dx.doi.org/10.2174/15701786113106660091