Status of Stem Cell Based Clinical Trials in the Treatment for Diabetes

Chandra      Viswanathan; Shabari      Sarang

doi:10.2174/15733998113096660082

Abstract

Rapidly increasing number of diabetic patients across the world is a great challenge to the current therapeutic approach. Although the traditional method of rendering exogenous insulin is an established method of treatment, it is not sufficient and often causes lethal hypoglycemia. There is also a good amount of success with whole organ transplantation or Islet cells’ transplantation. But this technique is limited with regards the availability of donors. Currently, many clinicians and researchers are involved in clinical studies using various different stem cells from embryonic as well as adult sources for the treatment of diabetes. In this review we have tried to discuss the results of various clinical trials using stem cells. We have also tried to look at various stem cell types and the routes of injections that are currently being followed world wide.

Keywords: Clinical trials, diabetes, stem cells, mesenchymal stem cells.