Three-Component Synthesis of Spiro[Indoline-3,4'-Pyrano[3,2-b]Pyran]- 2,8'-Diones Using a One-Pot Reaction

Title:Three-Component Synthesis of Spiro[Indoline-3,4'-Pyrano[3,2-b]Pyran]- 2,8'-Diones Using a One-Pot Reaction

Volume: 17 Issue: 2

Author(s): Abbas Rahmati, Zahra Khalesi and Tahmineh Kenarkoohi

Affiliation:

Keywords: Isatin, kojic acid, malononitrile, multi-component reaction, pyrano[3, 2-b]pyranone, pyranopyranone.

Abstract: A one-pot, three-component reaction of an isatin and kojic acid with an active methylene compound such as ethyl cyanoacetate, methyl cyanoacetate and malononitrile in methanol using catalytic amount of DABCO to give 2'- amino-6'-(hydroxymethyl)-8'H-spiro[indoline-3,4'-pyrano[3,2-b]pyran]-2,8'-diones in good to excellent yields under reflux conditions, is described.

Cite this article as:

Rahmati Abbas, Khalesi Zahra and Kenarkoohi Tahmineh, Three-Component Synthesis of Spiro[Indoline-3,4'-Pyrano[3,2-b]Pyran]- 2,8'-Diones Using a One-Pot Reaction, Combinatorial Chemistry & High Throughput Screening 2014; 17 (2) . https://dx.doi.org/10.2174/13862073113166660067

DOI https://dx.doi.org/10.2174/13862073113166660067	Print ISSN 1386-2073
Publisher Name Bentham Science Publisher	Online ISSN 1875-5402