Abstract
Tissue engineering and cell therapies are currently being leveraged to find improved treatment strategies in orthopaedics. Adipose stem cells have been considered for their potential to differentiate into different cell lineages. The potential of adipose stem cells to restore chondral, bone and tendon tissue has been demonstrated in vivo and in vitro studies. Recently their capacity to restore cells and extracellular matrix of the intervetebral disc has been also investigated. Treatment of several orthopedic diseases could benefit from the application of adipose stem cells. However, there is still lack of knowledge about their clinical use and further studies are needed to better clarify their potential.
Keywords: Adipose, stem, cells, orthopaedic, surgery.
Current Stem Cell Research & Therapy
Title:Potential of Adipose Derived Stem Cells in Orthopaedic Surgery
Volume: 8 Issue: 6
Author(s): Umile Giuseppe Longo, Giacomo Rizzello, Alessandra Berton, Mauro Ciuffreda, Filippo Migliorini, Wasim S. Khan and Vincenzo Denaro
Affiliation:
Keywords: Adipose, stem, cells, orthopaedic, surgery.
Abstract: Tissue engineering and cell therapies are currently being leveraged to find improved treatment strategies in orthopaedics. Adipose stem cells have been considered for their potential to differentiate into different cell lineages. The potential of adipose stem cells to restore chondral, bone and tendon tissue has been demonstrated in vivo and in vitro studies. Recently their capacity to restore cells and extracellular matrix of the intervetebral disc has been also investigated. Treatment of several orthopedic diseases could benefit from the application of adipose stem cells. However, there is still lack of knowledge about their clinical use and further studies are needed to better clarify their potential.
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Cite this article as:
Longo Giuseppe Umile, Rizzello Giacomo, Berton Alessandra, Ciuffreda Mauro, Migliorini Filippo, Khan S. Wasim and Denaro Vincenzo, Potential of Adipose Derived Stem Cells in Orthopaedic Surgery, Current Stem Cell Research & Therapy 2013; 8 (6) . https://dx.doi.org/10.2174/1574888X1130800058
DOI https://dx.doi.org/10.2174/1574888X1130800058 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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