Abstract
A simple and convenient one-pot multi-component reaction has been described for the synthesis of 3,4,5- substituted furan-2(5H)one from amines, aldehydes and dialkyl acetylenedicarboxylates in presence of sucrose. This method offers several advantages such as high yield, using sucrose as a cheap and readily available catalyst, readily available starting materials, and involving less hazardous chemical techniques.
Keywords: Amines, aldehydes, available catalyst, dialkyl acetylenedicarboxylates, cheap, less hazardous, multi-component reaction, one-pot, 3, 4, 5-substituted furan-2(5H)one, sucrose.
Graphical Abstract
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